Explanation of Bioreactor Components and Mechanisms

Bioreactor Parts

bioreactorchiller-diagram-06

Below is a list of bioreactor parts and descriptions of what they do

 Agitator

  • Used for mixing contents of reactor
  • Allows for better transport of nutrients
  • keeps particulates in a homogenous condition
  • Allows for transport of oxygen
  • Top riven or bottom driven
  • Magnetic or mechanically driven

Baffle

  • Break the vortex formation
  • Doesn’t allow center of gravity to become too powerful
  • Flat plate that controls or directs the flow of liquid

Sparger

  • Tube like device
  • Supplies air to aerobic bioreactors
  • Helps mixing of contents
  • Reduces power consumed

Jacket

  • Provides circulation of constant temperature
  • Uses a heat transfer skid and chilled water circulator
  • Keeps temperature of device at constant temperature

Controls

Temperature Measurement and Control

  • Measurement is done by thermocouple or sensor
  • Signals Temp Controller when needed
  • Controlled compares the set point to what was measured by sensor
  • Heating or cooling occurs depending upon the reading

pH Measurement and Control

  • Probe measures pH of bioreactor
  • Signal is compared with set point
  • Acid or alkali is activated

Foam Control

  • Used in fermentation
  • Controls foam that is created

Dissolved oxygen controller

  • Dissolved is measured by probe
  • Probe it is to be calibrated for its zero and hundred percent values
  • Instrument is calibrated by the measured value of dissolved